Renal Biomarkers

Please contact us to discuss our pricing options and possible academic discounts.

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Bio Assays

Renal Biomarkers

RBP; NAG; Creatinine; Albumin; Fibronectin; KIM 1; NGAL;

The detection of early renal biomarkers is essential for the early detection of kidney injury cause by drugs, surgery or decline in renal function as seen in chronic kidney disease (CKD).

We provide the following tests:

230001      Retinol Binding Protein (RBP)

  • an optimal biomarker for tubular proteinuria.
  • a sensitive indicator of tubule damage due to environmental toxins, such as Cadmium, and nephrotic antiviral drugs.
  • a constant feature of Fanconi’s syndrome, low levels indicate a carrier status of this hereditary disorder;
  • a more sensitive marker for the assessment of Multiple Myeloma with renal impairment than conventional indicators.
  • and a good marker of diabetic nephropathy.
  • more stable  than Beta-2-microglobulin avoiding pre-treatment of patients with buffers.
  • more sensitive than Beta-2-microglobulin.

We offer a customer centered  analysis service to meet your needs.

230002      N-Acetyl-β-D-glucosaminidase (NAG)

  • a sensitive and reliable indicator of the presence of renal disease and tubular damage.
  • a sensitive indicator of drug nephrotoxicity.
  • found in high levels in the urine during active disease or a sustain toxic insult but will fall with recovery or the removal of the toxin.

Can be used in conjunction with other tests to assess disease activity and prognosis.

230003      Creatinine

  • a breakdown product of creatine.
  • is removed from the body entirely by the kidneys.
  • is used as a reference substance for expressing excretion rate of various urinary metabolites.

We strongly recommend that is it measured in parallel with other urinary markers to give more confident and meaningful results.

230004      Albumin

  • Can be used to diagnose the condition of the kidney.
  • An albumin/creatinine ratio can be used to determine the level of damage to the kidneys.
  • In addition to chronic kidney disease urinary albumin has been demonstrated to be a marker of cardiovascular morbidity and mortality.

230005      Fibronectin (FN)

  • It is a matrix protein that is expressed throughout the body
  • It is one of the major matrix proteins in the kidney.
  • The accumulation of FN fragments in inflamed glomeruli could contribute to the progression of renal injury.
  • Urinary fibronectin levels are increased in patients with diabetic nephropathy and glomerular disease.

230006      Kidney Injury Molecule-1 (KIM-1)

  • a novel biomarker for nephrotoxicity
  • is an early and specific biomarker for tubular kidney injury.

230007      Neutrophil gelatinase associated lipocalin (NGAL)

  •  an indicator of acute kidney injury but also can be raised in infection.

 

 Contact us for more information or a quote on any of the above renal biomarkers.