Services References

RBP

Sensitive assays for urinary Retinol Binding Protein and β-2-Glycoprotein, based on commercially available standards.
Lapsley M, Akers K, Norden AGW
Ann. Clin. Biochem., 35:115-119. 1998

Tubular proteinuria defined by a study of Dent’s (CLCN5 mutation) and other tubular diseases
Norden AGW,  Asplin J, Deschodt-Lanckman MM, Langman C, Lapsley M, Nortier J,  Scheinman SJ, Thakker RV, Unwin RJ, Wrong OM
Kidney International 57, 240-9. 2000

Glomerular protein sieving and implications for renal failure in Fanconi syndrome.
Norden AG, Lapsley M, Lee PJ, Pusey CD, Scheinman SJ, Tam FW, Thakker RV, Unwin RJ, Wrong O.
Kidney Int. 2001 Nov;60(5):1885-1892.

Analysis of molecular forms of urine Retinol-Binding Protein in Fanconi Syndrome and design of an accurate immunoassay.
Keith A. Burling , Pedro R. Cutillas , David Church, Marta Lapsley , Anthony G.W. Norden .  Clinica Chimica Acta 413 483–489. 2012 February

NAG

Measurement of N-Acetyl-β-D-glucosaminidase and its isoenzymes in urine methods and clinical applications.
Price R.
Eur J Clin Chem Cin Biochem., 1992 Oct; 30(10); 693-705

The role of NAG (N-Acetyl-β-D-glucosaminidase) in the diagnosis of kidney disease in the monitoring of nephrotoxicity.
Price R.
Clin Nephrol 1992; 38 suppl. S14-19

Albumin

Laboratory issues in measuring and reporting urine albumin
Miller G and Bruns D.
Nephrol Dial Transplant (2009) 24: 717–718

Creatinine

Creatinine in Urine as an Index of Urinary Excretion Rate   S Jackson  Health Phsyics June 1966 – Volume 12 – Issue

Fibronectin

Elevated Urinary Fibronectin Excretion Predicts Poor Outcome in Patients with Primary Chronic Glomerulonephritis
Idasiak-Piechocka I et al
Nephron Clin Pract 2010;116:c47-c52

KIM-1

Kidney injury molecule-1 outperforms traditional biomarkers of kidney injury in preclinical biomarker qualification studies.
Vaidya V et al.
Nature biotechnology vol 28 number 5, May 2010

NGAL

Neutrophil gelatinase-associated lipocalin (NGAL) as a biomaker for acute renal injury after cardiac surgery.
Mishra J et al.
Lancet 365: 1231-1238. 2005

Iohexol

Development of an outpatient finger-prick glomerular filtration procedure suitable for epidemiological studies.
Niculescu-Duvaz I, D’mello L, Mann Z, Barron J, Newman D, Dockrell ME, Kwan J.
Kidney International
2006 April; 69 (7): 1272-1275

A practical method of measuring glomerular filtration rate by Iohexol clearance using direct capillary blood spots.
Mafham MM, Niculescu-Duvz I, Barron J, Emberson JR, Dockrell ME, Landray MJ, Balgent C.
Nephron Clin Pract
2007; 106 (3): c104-112

Cystatin C

Cystatin C
Newman D
Ann Clin Biochem 2002; 39: 89-104

Cystatin C: What more do we need to know?
Newman D.
Nephron Clin Prat 2003;93:c122-123